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1318 HYPOXIC MICROENVIRONMENT PROMOTES PI3K/AKT/MTOR SIGNALING PATHWAYS IN HUMAN CASTRATION RESISTANT PROSTATE CANCER

✍ Scribed by Yasumizu, Yota; Kosaka, Takeo; Miyazaki, Yasumasa; Kikuchi, Eiji; Miyajima, Akira; Oya, Mototsugu


Book ID
123189592
Publisher
Lippincott Williams and Wilkins
Year
2013
Tongue
English
Weight
52 KB
Volume
189
Category
Article
ISSN
0022-5347

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Magnolol induces apoptosis via inhibitin
✍ Dae-Hee Lee; Miroslaw-Jerzy Szczepanski; Yong J. Lee πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 413 KB

## Abstract We observed that treatment of prostate cancer cells for 24 h with magnolol, a phenolic component extracted from the root and stem bark of the oriental herb __Magnolia officinalis__, induced apoptotic cell death in a dose‐ and time‐dependent manner. A sustained inhibition of the major su