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Roles of the PI3K/Akt pathway and autophagy in TLR3 signaling-induced apoptosis and growth arrest of human prostate cancer cells

✍ Scribed by Nanae Harashima; Tohko Inao; Ryu Imamura; Shinji Okano; Takashi Suda; Mamoru Harada

Book ID
113026899
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
591 KB
Volume
61
Category
Article
ISSN
0340-7004

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## Abstract We observed that treatment of prostate cancer cells for 24 h with magnolol, a phenolic component extracted from the root and stem bark of the oriental herb __Magnolia officinalis__, induced apoptotic cell death in a dose‐ and time‐dependent manner. A sustained inhibition of the major su