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130 p53 Gene mutations in porokeratosis and squamous cell carcinoma arising in porokeratosis

✍ Scribed by Ninomiya, Y.; Sasaki, S.; Kubo, Y.; Urano, Y.; Arase, S.

Book ID
123592467
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
121 KB
Volume
10
Category
Article
ISSN
0923-1811

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Previous studies of oral cancer have suggested that alterations of the p53 tumour suppressor gene occur early in the precancerous stage of development. However, these observations have been based on cross-sectional assessment of abnormal p53 protein staining by immunohistochemistry and may not neces