1,3-Dipolar cycloadditions of cyclopentadienones with nitrile TV-oxides
β Scribed by N. G. Argyropoulos; N. E. Alexandrou
- Book ID
- 112125681
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1979
- Tongue
- English
- Weight
- 274 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0022-152X
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π SIMILAR VOLUMES
The scope and limitations of dipolar cycloaddition reactions between nitrile oxides/nitrones and prop-1-ene-1,3-sultone have been investigated. A remarkably high degree of regioselectivity and stereoselectivity was observed. The homochiral sultam 8e was synthesized in a four-step reaction sequence s
## Abstract The readily available alkyl dicyanoacetates 1 reacted with the 1,3βdipolar reagents arenecarbonitrile oxides 2β² and arenecarbonitrile imines 5β² to afford 1,2,4βoxadiazol and 1,2,4βtriazol derivatives. The arenecarbonitrile oxides 2β² with electronβdonating groups on the arene ring gave p