A study of the stereochemistry of the acid-catalyzed cyclization between (-)-8tosylaminomenthol (derived from (+)-pulegone) and acrolein diethyl acetal afforded two novel chiral perhydro-1,3-benzoxazine isomers 4a and 4b. Catalyst type as well as the reaction conditions dramatically affected the iso
1,3-Dipolar cycloaddition of nitrile oxides with cis- and trans-ethylene-substituted .DELTA.2-isoxazoline derivatives
β Scribed by Abu-Orabi, Sultan T.; Al-Ghezawi, Nawash M.
- Book ID
- 126836387
- Publisher
- American Chemical Society
- Year
- 1987
- Tongue
- English
- Weight
- 213 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0021-9568
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π SIMILAR VOLUMES
4,5-Dihydro-2-methyloxazole la and 4,5-dihydro-2,4.4-trimethyloxazole lb, which are examples of cyclic imidate esters, undergo 1,fdipolar cycloaddition reactions with benzonitrile N-oxide, to give the appropriate 5,6-dihydro-7a-methyl-3-
Novel aza-bicyclic 2-isoxazolines, 4,5-dihydroisoxazole [5,4-b]pyrrolidines, and 4,5-dihydroisoxazole[5,4b]piperidines were synthesized in a highly regioselective manner through a 1,3-dipolar cycloaddition reaction of 5-and 6-membered endocyclic enecarbamates and enamides with several nitrile oxides