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1,3-Dipolar Cycloaddition of D-Xylose Derived Nitrone with Methyl Acrylate. Synthesis of Chiral Pyrrolidinones and Pyrrolidines

✍ Scribed by Fišera, Lubor; Podolan, Gabriel; Fronc, Marek; Kožíšek, Jozef


Book ID
118267082
Publisher
Japan Institute of Heterocyclic Chemistry
Year
2012
Tongue
English
Weight
941 KB
Volume
84
Category
Article
ISSN
0385-5414

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## Abstract magnified image Asymmetric 1,3‐dipolar cycloadditions of chiral nitrones to 1‐propene‐1,3‐sultone (**1**) were investigated. Chiral nitrones **6a‐e** reacted with sultone **1** in toluene at 90 °C for 24‐36 h to give the corresponding isoxazolidines in moderate yields with high regiose