Diastereoselective synthesis of pyrrolid
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K. Karthikeyan; R. Senthil Kumar; D. Muralidharan; P.T. Perumal
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Article
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2009
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Elsevier Science
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French
⚖ 691 KB
1,3-Dipolar cycloaddition of D-glucose-derived azomethine ylides for the synthesis of chiral pyrrolidines accompanied an unexpected 1,2-elimination in the furanose moiety of the products. The C3 0 alkoxy/ hydroxy group of the furanose moiety was invariably eliminated under the reaction conditions. A