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Asymmetric construction of substituted pyrrolidines via 1,3-dipolar cycloaddition of azomethine ylides and chiral acrylates derived from biomass

✍ Scribed by Llompart, David F.; Sarotti, Ariel M.; Corne, Valeria; Suárez, Alejandra G.; Spanevello, Rolando A.; Echeverría, Gustavo A.; Piro, Oscar E.; Castellano, Eduardo E.


Book ID
121698617
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
638 KB
Volume
55
Category
Article
ISSN
0040-4039

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Diastereoselective synthesis of pyrrolid
✍ K. Karthikeyan; R. Senthil Kumar; D. Muralidharan; P.T. Perumal 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 691 KB

1,3-Dipolar cycloaddition of D-glucose-derived azomethine ylides for the synthesis of chiral pyrrolidines accompanied an unexpected 1,2-elimination in the furanose moiety of the products. The C3 0 alkoxy/ hydroxy group of the furanose moiety was invariably eliminated under the reaction conditions. A