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1,3-dipolar cycloaddition of benzonitrile oxide with vinylsilanes

✍ Scribed by Albert Padwa; J.Gavin MacDonald


Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
208 KB
Volume
23
Category
Article
ISSN
0040-4039

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✦ Synopsis


The reaction of benzonitrile oxide with several vinylsilanes has been found to afford silylated isoxazoles.

Relative rates for the cycloaddition reaction were determined.


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1,3-Dipolar Cycloaddition of Benzonitril
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## Abstract Benzonitrile oxide cycloadds to the Cο£ΎC bond of substituted 4,5‐dihydro‐3‐methylene‐2(3__H__)‐furanones 1a–1g. Thus, (__E__)‐1a and (__E__)‐1b are converted into the corresponding isoxazolinespirodihydrofuranones (4__RS__,5__RS__)‐2a and (4__RS__,5__RS__)‐2b, and (__E__)‐1c is converted