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12q13, A new recurrent breakpoint in acute non-lymphoblastic leukemia

✍ Scribed by Marieke M.B. Seyger; Jutta Ritterbach; Ursula Creutzig; Astrid K. Gnekow; Ulrich Göbel; Norbert Graf; Alfred Reiter; Fritz Lampert; Jochen Harbott

Book ID
113253372
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
524 KB
Volume
80
Category
Article
ISSN
0165-4608

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✍ Hazel M. Robinson; Kerry E. Taylor; G. Reza Jalali; Kan Luk Cheung; Christine J. 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 746 KB

The recurrent t(14;19)(q32;q13) translocation associated with chronic B-cell lymphoproliferative disorders, such as atypical chronic lymphocytic leukemia, results in the juxtaposition of the IGH@ and BCL3 genes and subsequent overexpression of BCL3. We report six patients with B-cell precursor acute