✦ LIBER ✦

1289 A MECHANISM FOR ANDROGEN-INDEPENDENT PROSTATE CANCER THROUGH MODULATION OF ANDROGEN RECEPTOR SIGNALING BY THE P21-ACTIVATED KINASE 6 (PAK6)

✍ Scribed by Zhang, Min; Siedow, Michael; Saia, Gregory; Chakravarti, Arnab

Book ID: 121935441
Publisher: Lippincott Williams and Wilkins
Year: 2010
Tongue: English
Weight: 41 KB
Volume: 183
Category: Article
ISSN: 0022-5347
DOI: 10.1016/j.juro.2010.02.873

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A mechanism for hormone-independent pros

A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase

✍ Sawyers, Charles L.; Craft, Noah; Shostak, Yuriy; Carey, Michael 📂 Article 📅 1999 🏛 Nature Publishing Group 🌐 English ⚖ 202 KB

Steroid-independent activation of androg

Steroid-independent activation of androgen receptor in androgen-independent prostate cancer: A possible role for the MAP kinase signal transduction pathway?

✍ X Zhu; J.-P Liu 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 358 KB

Re: p21-Activated Kinase 6 (PAK6) Inhibi

Re: p21-Activated Kinase 6 (PAK6) Inhibits Prostate Cancer Growth via Phosphorylation of Androgen Receptor and Tumorigenic E3 Ligase Murine Double Minute-2 (Mdm2)

✍ Atala, Anthony 📂 Article 📅 2013 🏛 Lippincott Williams and Wilkins 🌐 English ⚖ 75 KB

Constitutive activation of the androgen

Constitutive activation of the androgen receptor by a point mutation in the hinge region: A new mechanism for androgen-independent growth in prostate cancer

✍ Jocelyn Céraline; Marion D. Cruchant; Eva Erdmann; Philippe Erbs; Jean-Emmanuel 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 278 KB 👁 2 views

## Abstract Androgen receptor (AR) mutations that modify both the ligand binding and the transactivation capacities of the AR represent one of the mechanisms involved in the transition of prostate cancer (PCa) from androgen‐dependent to androgen‐independent growth. We use a yeast‐based functional a