1,2,5-Oxadiazole N -Oxide Derivatives and Related Compounds as Potential Antitrypanosomal Drugs: Structure−Activity Relationships
✍ Scribed by Cerecetto, Hugo; Di Maio, Rossanna; González, Mercedes; Risso, Mariela; Saenz, Patricia; Seoane, Gustavo; Denicola, Ana; Peluffo, Gonzalo; Quijano, Celia; Olea-Azar, Claudio
- Book ID
- 120181147
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 170 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0022-2623
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Several new 1,2,5-oxadiazole N-oxide derivatives were synthesized to be tested both as potential selective hypoxic cell cytotoxins and as DNA-binding agents. The compounds prepared included bis(1,2,5-oxadiazole N-oxide) derivatives and oxadiazole rings linked to naphthyl residues. The compounds were
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