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1,25-(OH)2-Vitamin D3 Suppresses the Bone-Related Runx2/Cbfa1 Gene Promoter

✍ Scribed by Hicham Drissi; Arlyssa Pouliot; Christian Koolloos; Janet L. Stein; Jane B. Lian; Gary S. Stein; André J. van Wijnen

Book ID
115604233
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
317 KB
Volume
274
Category
Article
ISSN
0014-4827

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✍ Hicham Drissi; Arlyssa Pouliot; Janet L. Stein; Andre J. van Wijnen; Gary S. Ste 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB 👁 1 views

The runt homology transcription factor Runx2/Cbfa1 is essential for bone development and osteoblast differentiation. Regulatory mechanisms that govern Runx2 transcription in osteoblasts define the osteogenic pathways that control skeletal development. In this study, we systematically examined transc