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Transcriptional regulation of the human Runx2/Cbfa1 gene promoter by bone morphogenetic protein-7

โœ Scribed by Liqiang Tou; Naureen Quibria; Joseph M Alexander


Book ID
117463365
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
400 KB
Volume
205
Category
Article
ISSN
0303-7207

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The runt homology transcription factor Runx2/Cbfa1 is essential for bone development and osteoblast differentiation. Regulatory mechanisms that govern Runx2 transcription in osteoblasts define the osteogenic pathways that control skeletal development. In this study, we systematically examined transc