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1,25-Dihydroxyvitamin D3inhibits parathyroid hormone-related peptide mRNA expression in fetal rat long bones in culture

✍ Scribed by Rafik Karmali; Nicole Nijs-DeWolf; Ingo Beyer; Geoffrey N. Hendy; Pierre Bergmann

Book ID: 107427655
Publisher: Society for In Vitro Biology
Year: 1999
Tongue: English
Weight: 300 KB
Volume: 35
Category: Article
ISSN: 1475-2689
DOI: 10.1007/s11626-999-0074-9

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## Abstract It is known that pharmacological or toxic doses of vitamin D induce bone resorption both in vivo and in vitro, whereas physiological doses of the vitamin have a protective effect on bone in vivo. To investigate the discrepancies of the dose‐dependent effect of vitamin D on bone resorpti