## Abstract The purpose of our study was to prospectively evaluate cardiac [^123^I]metaiodobenzylguanidine (MIBG) uptake in patients with cerebrovascular disease (CVD) who develop clinical symptoms of vascular Parkinsonism (VP). A total of 19 consecutive patients who developed Parkinsonism during t
123I-metaiodobenzylguanidine scintigraphy of ectopic intracranial retinoblastoma
β Scribed by Bomanji, J. ;Kingston, J. E. ;Hungerford, J. L. ;Britton, K. E.
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 672 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0098-1532
No coin nor oath required. For personal study only.
β¦ Synopsis
Radioiodinated metaiodobenzylguani-
with ectopic intracranial retinoblastoma. It is felt that 1231 MlBC scintigraphy may have a role in detecting occult metastatic disease in these patients.
dine (MIBG) has been used for diagnostic purposes to image neural crest tumors. We report the uptake of lZ3l MlBC in a child
π SIMILAR VOLUMES
## Abstract Autonomic dysfunction is common in Lewy body disorders (Parkinson's disease, Dementia with Lewy Bodies, Pure Autonomic Failure, and REM sleep disorder). The loss of postβganglionic myocardial sympathetic nerve fibers is a prominent feature of autonomic dysfunction in such disorders. ^12
Although we are sympathetic to Reynolds and Slocum's concerns, 1 their editorial errs on several points. The authors cite deference to regulatory (presumably Food and Drug Administration) approval as a constraint. The FDA has long recognized broad physician discretion in using FDAapproved drugs or d
## SUmARY We have examined the labelling of [1231] HIBG by a Cu(1) catalyzed reaction in aqueous solution. We regularly obtained >99% radiochemical purity [1231] MIBG product and >97% radiochemical yield. At 100Β°C with 2 mg MIBG the radiochemical purity reached 85% at 2.5 Pin, 97% at 5 min and 99%
Metaiodobenzylguanidine (MIBG) is actively concentrated in adrenergic neuroendocrine tissues and tumors by an active, energy- and sodium-dependent, high-affinity, saturable mechanism. This has proved successful, when labeled with 131-I or 123-I, in scintigraphically depicting pheochromocytomas and n
## Abstract Patients with parkinsonism pose a diagnostic challenge. Parkinson's disease may be difficult to distinguish from multiple system atrophy and progressive supranuclear palsy, whereas Parkinson's disease and dementia with Lewy bodies can be difficult to distinguish from Alzheimer's disease