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1,2,3-Triazolo[4,5-d]-1,2,4-triazolo[4,3-b]pyridazines

✍ Scribed by Giuliana Biagi; Irene Giorgi; Oreste Livi; Clementina Manera; Valerio Scartoni


Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
306 KB
Volume
34
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

Some new 1,2,3‐triazolo[4,5‐d]‐1,2,4‐triazolo[4,3‐b]pyridazines were prepared starting from the corresponding 1,2,3‐triazolo[4,5‐d]pyridazines via the formation of the 1,2,4‐triazole ring, by condensation of an appropriate monocarbon fragment with the 4‐hydrazino substituent and the nitrogen atom in the 5 position of the heterocycle. Condensation of 4‐phenylhydrazino substituted derivatives with formic acid gave zwitterionic compounds.


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New 1,2,3-triazolo[4,5-d]1,2,4-triazolo[
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## Abstract New tricyclic 1,2,3‐triazolo‐1,2,4‐triazolo‐pyridazine derivatives, bearing a methyl substituent on the 1,2,3‐triazole ring, were prepared as potential biological agents. __N__‐Methylation of dimethyl 1,2,3‐triazole‐4,5‐dicarboxylate allowed synthesis of the isomeric 1‐methyl‐4,7‐dihydr

1,2,3-Triazolo[4,5-e]-1,2,4-triazolo[3,4
✍ Giuliana Biagi; Irene Giorgi; Oreste Livi; Clementina Manera; Valerio Scartoni 📂 Article 📅 1999 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 301 KB

## Abstract Some new 1,2,3‐triazolo[4,5‐__e__]‐1,2,4‐triazolo[3,4‐__c__]pyrimidmes were prepared starting from the corresponding 1,2,3‐triazolo[4,5‐__d__]pyrimidines __via__ the formation of the 1,2,4‐triazole ring. Thus suitable hydrazino derivatives 6 were condensed with triethyl orthoformate, tr