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12 TLR2 and TLR4 Signaling Regulates ENS Integrity and Intestinal Function

✍ Scribed by Brun, Paola; Qesari, Marsela; Spagnol, Lisa; Porzionato, Andrea; Galeazzi, Francesca; Sturniolo, Giacomo C.; Castagliuolo, Ignazio; Giron, Maria Cecilia

Book ID
123319238
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
458 KB
Volume
144
Category
Article
ISSN
0016-5085

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## Abstract The family of Toll‐like receptors (TLRs) expressed by innate immune cells recognizes a spectrum of microbial components as well as molecules released from injured tissues. TLR ligation activates intracellular signaling cascades that culminate in the up‐regulation of proinflammatory gene