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Transcriptional Integration of TLR2 and TLR4 Signaling at the NCoR Derepression Checkpoint

✍ Scribed by Wendy Huang; Serena Ghisletti; Valentina Perissi; Michael G. Rosenfeld; Christopher K. Glass


Book ID
116754707
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
932 KB
Volume
35
Category
Article
ISSN
1097-2765

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## Abstract Severe injury deranges immune function and increases the risk of sepsis and multiple organ failure. Kupffer cells play a major role in mediating posttraumatic immune responses, in part via different Toll‐like receptors (TLR). Although mitogen‐activated protein kinases (MAPK) are key ele