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1,2-dihydroisoquinolines—VI: The benzylation of isoquinoline derivatives

✍ Scribed by M. Sainsbury; S.F. Dyke; D.W. Brown; W.G.D. Lugton

Book ID
103399498
Publisher
Elsevier Science
Year
1968
Tongue
French
Weight
773 KB
Volume
24
Category
Article
ISSN
0040-4020

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A One-Pot Synthesis of 1,2-Dihydroisoqui
A One-Pot Synthesis of 1,2-Dihydroisoquinoline Derivatives from Isoquinoline via a Four-Component Reaction
✍ Abdolali Alizadeh; Nasrin Zohreh 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 German ⚖ 168 KB 👁 1 views

## Abstract A four‐component reaction for the synthesis of 1,2‐dihydroisoquinoline derivatives is described. The __Huisgen__ 1,4‐dipolar intermediate, which is produced from isoquinoline and an electron‐deficient acetylene compound **1**, reacts with H~2~O in the presence of diketene to produce 1,2