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11C-labelling of Ro 15-1788 in two different positions, and also 11C-labelling of its main metabolite Ro 15-3890, for PET studies of benzodiazepine receptors

✍ Scribed by Christer Halldin; Sharon Stone-Elander; Jan-Olov Thorell; Anders Persson; Göran Sedvall

Publisher
Elsevier Science
Year
1988
Weight
270 KB
Volume
39
Category
Article
ISSN
0883-2889

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The determination of the percentage of unchanged [11C]Ro 15-1788 with respect to total radioactivity, essential for the pharmacokinetic exploitation of data of blood radioactivity decrease obtained in PET studies, may be carried out with equal results using either an extraction procedure or a TLC me