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11C-labelled etorphine for “in vivo” studies of opiate receptors in brain

✍ Scribed by M. Maziere; J. M. Godot; G. Berger; C. Prenant; D. Comar

Book ID
112764829
Publisher
Springer
Year
1981
Tongue
English
Weight
251 KB
Volume
62
Category
Article
ISSN
1588-2780

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A method is described for the preparation of [11C]buprenorphine in high specific activity, based on the reaction of N-(de-cyclopropylmethyl)buprenorphine with "no carrier added" [1-11C]cyclopropanecarbonyl chloride followed by reduction with lithium aluminium hydride. The [1-11C]cyclopropanecarbonyl