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118 Poor differentiation in malignant serous ovarian tumors is accompanied by stromal expression of the urokinase plasminogen activator

✍ Scribed by Christer Borgfeldt; Bertil Casslé; Ingegerd Lecander

Book ID
117439496
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
131 KB
Volume
11
Category
Article
ISSN
0268-9499

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High tissue content of urokinase plasmin
High tissue content of urokinase plasminogen activator (u-PA) is associated with high stromal expression of u-PA mRNA in poorly differentiated serous ovarian carcinoma
✍ Christer Borgfeldt; Bertil Casslén; Chun-Li Liu; Stefan Hansson; Ingegerd Lecand 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 842 KB

Urokinase plasminogen activator (u-PA) plays a pivotal role in tissue degradation during tumor spread and metastasis. We have quantitated u-PA in tissue homogenates of 31 serous ovarian tumors and localized u-PA and its mRNA in tissue sections of 26 serous ovarian tumors. The content of u-PA was hig