𝔖 Bobbio Scriptorium
✦   LIBER   ✦

111In-bleomycin imaging of breast tumours

✍ Scribed by Seppo Soimakallio; Aaro Kiuru

Publisher
Springer
Year
1980
Tongue
English
Weight
264 KB
Volume
5
Category
Article
ISSN
0340-6997

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✦ Synopsis

Forty female patients with 15 malignant breast tumours and 25 benign growths, all verified histologically, were studied before surgery using mammography and 111In-Bleomycin scintigraphy. The patient was studied lying prone on a table with an opening so that one breast could hang in front of the gamma camera. The true positive and negative scintigraphy results are slightly poorer (70%) than the mammography results (80%) and there are more false negative scintigraphy interpretations mostly in small lesions.

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## Abstract We have found a new ^111^In‐bleomycin complex (BLMC), which has high affinity to tumor, does not bind to transferrin and is stable in vivo. Distribution in animals bearing glioma, hepatoma, or mammary adenocarcinoma at 48 hours showed: the ratios of tumor to blood, brain, heart, lung, l