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11 Response to Infliximab Treatment in Crohn’s Disease is Correlated with Increased Soluble IL-15Rα Serum Levels

✍ Scribed by Gregory Bouchaud; Erwan Mortier; Arnaud Bourreille; Ariane Plet; Yannick Jacques


Book ID
116397903
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
48 KB
Volume
39
Category
Article
ISSN
1043-4666

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## Background: We analyzed the influence of Crohn's disease (CD)associated IL23R gene variants on IL-22 that is expressed in IL-23Rϩ Th17 cells. Methods: IL-22 serum levels were measured in 242 CD patients and in 31 healthy controls. Subanalyses included serum levels of IL-6, TNF-␣, IL-17A, IL-17