The structures of two solid inclusion compounds with the 2',6'-dimethoxyflavone host molecule (1) were investigated by single-crystal x-ray analysis. Both compounds, 1 Á trichloroacetic acid (1:1) and 1 Á chloroacetic acid (1:1) crystallize in non-centrosymmetric groups Pna2 1 and P2 1 2 1 2 1 , res
1:1 Crystal complex of 2′,6′-dimethoxyflavone and 2,6-dimethoxybenzoic acid. Relationship of pKa to x-ray hydrogen bond data
✍ Scribed by J.-C. Wallet; E. Molins; C. Miravitlles
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 123 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0894-3230
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✦ Synopsis
The crystal structure of the 2',6'-dimethoxyflavone-2,6-dimethoxybenzoic acid complex was determined. Owing steric hindrance of the methoxy groups, the two H-bonded molecules are twisted. Earlier results were used to establish a relationship between the pK a values of different acids and their hydrogen bond distances in complexes with 2',6'-dimethoxyflavone.
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