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1,1-Bis(3'-indolyl)-1-(p-substituted phenyl) methanes induce autophagic cell death in estrogen receptor negative breast cancer

✍ Scribed by Kathy Vanderlaag; Yunpeng Su; Arthur E Frankel; Robert C Burghardt; Rola Barhoumi; Gayathri Chadalapaka; Indira Jutooru; Stephen Safe


Book ID
115010306
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
781 KB
Volume
10
Category
Article
ISSN
1471-2407

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1,1-bis(3′-indolyl)-1-(p-substituted phe
✍ Jun Hong; Ismael Samudio; Sudhakar Chintharlapalli; Stephen Safe 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 748 KB

## Abstract 1,1‐Bis(3′‐indolyl)‐1‐(__p__‐substituted phenyl)methanes, containing __p‐t‐__butyl (DIM‐C‐pPhtBu) and phenyl (DIM‐C‐pPhC~6~H~5~) substituents, are peroxisome proliferator‐activated receptor γ (PPARγ) agonists; however, DIM‐C‐pPhtBu‐induced growth inhibition and cell death in human HEC1A