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1088 POSTER Liposome-Encapsulated Hemoglobin Enhances Radiotherapy and Chemotherapy to Suppress Tumour Growth and Metastasis in Mice

✍ Scribed by C. Murayama; A.T. Kawaguchi; K. Ishikawa; A. Kamijo; S. Sadahiro; Y. Nagato

Book ID: 117661225
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 42 KB
Volume: 47
Category: Article
ISSN: 0959-8049
DOI: 10.1016/s0959-8049(11)70731-6

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## Abstract We hypothesize that liposome‐encapsulated hemoglobin with high O~2~ affinity (P~50~0~2~ = 12 mm Hg, h‐LEH) may increase O~2~ delivery to hypoxic tumors and enhance radiation therapy synergistically to suppress tumor growth. First, h‐LEH (5, 10, and 20 mL/kg) was intravenously infused 30