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108. The C677T mutation of the 5, 10-methylenetetrahydropholate reductase gene (mthfr) and moderate hyperhomocysteinemia in young thrombophilic patients

✍ Scribed by F.P. Mancini; R. De Franchis; A. D'Angelo; G. Sebastio; I. Fermo; V. De Stefano; M. Margaglione; G. Mazzola; A.M. Cerbone; L. Soriente; G. Andria; G. Di Minno


Book ID
114201722
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
133 KB
Volume
10
Category
Article
ISSN
0268-9499

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A common haplotype for the 677T thermola
✍ M. Linnebank; A. Homberger; U. Nowak-GΓΆttl; H. G. Koch πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 18 KB

The common polymorphic transition 677C>T in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene causes a thermolabile enzyme variant. This variant is associated with moderate hyperhomocysteinemia, a risk factor for vascular disease and thrombophilia. Up to now, it remained unclear if the therm