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1054 PARK2 mutations in patients with early-onset Parkinson's disease


Book ID
123196780
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
125 KB
Volume
238
Category
Article
ISSN
0022-510X

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## Abstract Mutations in __LRRK2__ (__leucine‐rich repeat kinase 2__) have been associated with autosomal dominant Parkinson's disease (PD) and cluster in several 3β€² exons of the gene. The majority of mutations have been detected in late‐onset cases (age at onset >50 years). We screened 5 of the 51