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101: SWAP-70 is required for spontaneous transformation of mouse embryo fibroblasts

✍ Scribed by Chang, Y.T.; Shu, C.L.; Lai, J.Y.; Lin, C.Y.; Chuu, C.P.; Ichikawa, T.; Morishita, K.; Jessberger, R.; Fukui, Y.

Book ID
125802994
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
244 KB
Volume
50
Category
Article
ISSN
0959-8049

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## Abstract SWAP‐70 is a protein involved in actin rearrangement, especially in membrane ruffling. Mouse embryo fibroblasts (MEFs) deficient in SWAP‐70 show impaired membrane ruffling and fail to grow in soft agar after transformation by v‐Src. Here, we show that v‐Src transformed MEFs expressing S