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1‐ n ‐Butyl‐3‐Methylimmidazolium Tetrafluoroborate–Promoted Green Synthesis of 5‐Arylidene Barbituric Acids and Thiobarbituric Acid Derivatives

✍ Scribed by Wang, Chun; Ma, Jing‐jun; Zhou, Xin; Zang, Xiao‐huan; Wang, Zhi; Gao, Yong‐jun; Cui, Peng‐lei


Book ID
119938893
Publisher
Taylor and Francis Group
Year
2005
Tongue
English
Weight
82 KB
Volume
35
Category
Article
ISSN
0039-7911

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## Abstract A sodium derivative of 1,3‐dimefhylbarbituric acid or 1,3‐diethyl‐2‐thiobarbituric acid undergoes an efficient monoacylation at C5 by the reaction with ω‐chloroalkanoyl chloride or diacid dichloride in the presence of pyridine in tetrahydrofuran. A nucleophilic displacement of the chlor