1-Iodomethyl-3,4-diphenyl-2,6-dioxabicyclo[2.2.0]hexane: the first example of a [2.2.0] fused ketal

✍ Scribed by Gan Wang; Ying Wang; Joel T. Arcari; Amy R. Howell; Arnold L. Rheingold; Thomas Concolino

• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 182 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)01469-0

✦ Synopsis

The preparation of l-iodomethyl-3,4-diphenyl-2,6-dioxabicyclo[2.2.0]hexane ( 12) is described. This represents the first reported example of a [2.2.0] fused ketal. The key step involved the iodoetherification of a 2methyleneoxetane 11 containing a pendant alcohol.