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1-Deoxynojirimycin hydrochloride

✍ Scribed by Linden, A. ;Hoos, R. ;Vasella, A.


Book ID
114510835
Publisher
International Union of Crystallography
Year
1994
Tongue
English
Weight
477 KB
Volume
50
Category
Article
ISSN
0108-2701

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πŸ“œ SIMILAR VOLUMES


Synthesis of (1-13C)-1-deoxynojirimycin
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Asymmetric synthesis of (+)-1-deoxynojir
✍ Ulf M. LindstrΓΆm; Peter Somfai πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 205 KB

An asymmetric synthesis of (+)-l-deoxynojirimycin (1) in 14 steps starting from diene ( 5) is described. The key transformations in the sequence are a Sharpless dihydroxylation and epoxidation followed by a regio-and stereoselective aminolysis of vinyl epoxide 11 to give piperidine 12.

Lipophilic prodrugs of 1-deoxynojirimyci
✍ Sandra Fouace; Michel Therisod πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 122 KB

We report a new synthesis of Miglitol, and its conversion to a lipophilic prodrug. The same procedure permits the preparation of a prodrug of 1-desoxynojirimycin and probably of other 1-deoxynojirimycin derivatives.