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1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB1 or CB2 receptor ligands

✍ Scribed by Francesco Piscitelli; Alessia Ligresti; Giuseppe La Regina; Valerio Gatti; Antonella Brizzi; Serena Pasquini; Marco Allarà; Mauro Antonio Maria Carai; Ettore Novellino; Giancarlo Colombo; Vincenzo Di Marzo; Federico Corelli; Romano Silvestri

Book ID: 113583151
Publisher: Elsevier Science
Year: 2011
Tongue: French
Weight: 779 KB
Volume: 46
Category: Article
ISSN: 0223-5234
DOI: 10.1016/j.ejmech.2011.09.037

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## Abstract The feasibility of nucleophilic displacement of bromide in the 4‐bromopyrazole ring with [^18^F]fluoride has been demonstrated by the synthesis of two radiolabeled compounds: __N__‐(piperidin‐1‐yl)‐5‐(4‐methoxyphenyl)‐1‐(2‐chlorophenyl)‐4‐[^18^F]fluoro‐1__H__‐pyrazole‐3‐carboxamide, ([^