## Abstract Phenylpropionamides acylated in the ortho position with aralkanecarboxylic acids were cyclised to give, after reduction, 1‐aralkyl‐tetrahydro‐2‐benzazepines.
1-aralkylated tetrahydro-2-benzazepines. Part II: Synthesis from 3-(3,4-dimethoxyphenyl)-propylamine
✍ Scribed by Daniel Berney; Theodor Jauner
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- German
- Weight
- 280 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
3‐(3,4‐Dimethoxyphenyl)‐propylamine was N‐acylated with aralkanecarboxylic acid chlorides. The resulting amides were subjected to Bischler‐Napieralski ring closure to give the corresponding 1‐aralkyl‐dihydro‐2‐benzazepines. These were reduced to the title compounds.
📜 SIMILAR VOLUMES
## Abstract 1‐Benzyl‐tetrahydro‐2‐benzazepin‐3‐ones **4** were prepared by submitting the corresponding 1‐benzyl‐β‐tetralones **3** to the __Schmidt__ reaction. On the other hand, the rearrangement of the tetralones **3** by the __Beckmann__ procedure gave 1‐benzyl‐tetrahydro‐3‐benzazepin‐2‐ones **
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