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1-[(4aS,5R,7R,7aS)-7-Hydroxy­methyl-3,4,4a,5,7,7a-hexa­hydro-2H-furo[3,4-b][1,4]thia­zin-5-yl]pyrimidine-2,4(1H,3H)-dione

✍ Scribed by Sun, Jing-Bo ;Yang, Hua ;Wu, Jin-Chang


Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
145 KB
Volume
63
Category
Article
ISSN
1600-5368

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✦ Synopsis


The title compound, C 11 H 15 N 3 O 6 S, is a 2 0 ,3 0 -thiazine-fused bicyclic nucleoside. The furanose ring adopts a 3 0 -endo,4 0 -exo conformation 4 T 3 . The orientation of the pyrimidine ring is anti with respect to the sugar group. The crystal packing is stabilized by intermolecular N-HÁ Á ÁO hydrogen bonds.


📜 SIMILAR VOLUMES


4-(4-Chloro­phenyl)-1,7,7-tri­methyl-1,2
✍ Tu, Shujiang ;Zhu, Xiaotong ;Zhang, Jinpeng ;Xu, Jianing ;Wang, Qian 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 130 KB

The title compound, C 18 H 20 ClNO 2 , has been synthesized by the reaction of 4-chlorobenzaldehyde, Meldrum's acid, dimedone and CH 3 NH 3 Cl(NaOAc) in ethanol under microwave irradiation. The pyridone ring adopts a screw-boat conformation and the cyclohexenone ring an envelope conformation.