1-[(4aS,5R,7R,7aS)-7-Hydroxymethyl-3,4,4a,5,7,7a-hexahydro-2H-furo[3,4-b][1,4]thiazin-5-yl]pyrimidine-2,4(1H,3H)-dione
✍ Scribed by Sun, Jing-Bo ;Yang, Hua ;Wu, Jin-Chang
- Publisher
- International Union of Crystallography
- Year
- 2007
- Tongue
- English
- Weight
- 145 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
The title compound, C 11 H 15 N 3 O 6 S, is a 2 0 ,3 0 -thiazine-fused bicyclic nucleoside. The furanose ring adopts a 3 0 -endo,4 0 -exo conformation 4 T 3 . The orientation of the pyrimidine ring is anti with respect to the sugar group. The crystal packing is stabilized by intermolecular N-HÁ Á ÁO hydrogen bonds.
📜 SIMILAR VOLUMES
The title compound, C 18 H 20 ClNO 2 , has been synthesized by the reaction of 4-chlorobenzaldehyde, Meldrum's acid, dimedone and CH 3 NH 3 Cl(NaOAc) in ethanol under microwave irradiation. The pyridone ring adopts a screw-boat conformation and the cyclohexenone ring an envelope conformation.