The title compound, C 19 H 16 BrN 3 O, was synthesized by the reaction of 5-amino-3-methyl-1-phenylpyrazole with 4-bromophenylaldehyde and Medrum's acid in glycol under microwave irradiation. X-ray crystal structure analysis reveals three crystallographically independent molecules in the asymmetric
1-[4-(Hexyloxy)phenyl]pyridin-4(1H)-one monohydrate
✍ Scribed by Robinson, Paul D. ;Li, Chenguang ;Wolf, Jeremy R. ;Dyer, Daniel J.
- Publisher
- International Union of Crystallography
- Year
- 2005
- Tongue
- English
- Weight
- 379 KB
- Volume
- 61
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
Structure analysis of the title compound, C 17 H 21 NO 2 ÁH 2 O, containing a polar 4-pyridone moiety, demonstrates that bifurcated acceptor hydrogen bonds involving water molecules as hydrogen-bonding donors and C O groups as hydrogen-bonding acceptors form infinite one-dimensional molecular chains.
📜 SIMILAR VOLUMES
The crystal structure of the title compound, C~17~H~15~FN~2~O~2~, was determined as part of a study of the biological activity of pyridine-substituted isoxazole derivatives as mitogen-activated protein kinase (MAPK) inhibitors. In the crystal structure of the title compound, the compound exists in t