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094 INCREASED EXPRESSION OF ARTHRITIC MARKER GENES IN THE CARTILAGE OF SIRT1 NULL MICE

โœ Scribed by O.H. Gabay; E. Lee; R. Booth; V. Gagarina; M. Dvir-Ginzberg; D.J. Hall


Book ID
114351875
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
74 KB
Volume
18
Category
Article
ISSN
1063-4584

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## Abstract ## BACKGROUND Hox transcription factors are well known for their role in skeletal patterning in vertebrates. They regulate gene expression during the development of cartilage, the precursor to mature bone. We previously reported that overexpression of the homeobox genes __Hoxc8__ and _