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04A An evaluation of new designs for phase I clinical trials

โœ Scribed by Tamara Odom-Maryon; Chul Ahn; Joyce C. Niland


Book ID
113297970
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
53 KB
Volume
15
Category
Article
ISSN
0197-2456

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Phase I clinical trials are designed to identify an appropriate dose for experimentation in phase II and III studies. I present the results from a simulation study to evaluate the performance of nine phase I designs involving the standard design, the two-stage modified Storer's design, the two-stage