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0020: Role of HIF-1 in the cardiac remodeling and inotropic effects of chronic intermittent hypoxia

✍ Scribed by Gras, Emmanuelle; Lemarié, Emeline; Carmeliet, Peter; Lévy, Patrick; Godin-Ribuot, Diane

Book ID: 125798260
Publisher: Elsevier
Year: 2014
Tongue: English
Weight: 52 KB
Volume: 6
Category: Article
ISSN: 1878-6480
DOI: 10.1016/S1878-6480(14)71414-4

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## Abstract Oxygen‐dependent regulation of HIF‐1 activity occurs at multiple levels in vivo. The mechanisms regulating HIF‐1α protein expression have been most extensively analyzed but the ones modulating HIF‐1 transcriptional activity remain unclear. Changes in the phosphorylation and/or redox sta