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0020: Role of HIF-1 in the cardiac remodeling and inotropic effects of chronic intermittent hypoxia

✍ Scribed by Gras, Emmanuelle; Lemarié, Emeline; Carmeliet, Peter; Lévy, Patrick; Godin-Ribuot, Diane


Book ID
125798260
Publisher
Elsevier
Year
2014
Tongue
English
Weight
52 KB
Volume
6
Category
Article
ISSN
1878-6480

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## Abstract Oxygen‐dependent regulation of HIF‐1 activity occurs at multiple levels in vivo. The mechanisms regulating HIF‐1α protein expression have been most extensively analyzed but the ones modulating HIF‐1 transcriptional activity remain unclear. Changes in the phosphorylation and/or redox sta