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ω-Transaminases for the Production of Optically Pure Amines and Unnatural Amino Acids

✍ Scribed by Mathew, Sam; Yun, Hyungdon

Book ID
115504822
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
870 KB
Volume
2
Category
Article
ISSN
2155-5435

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Asymmetric Synthesis of Optically Pure Pharmacologically Relevant Amines Employing ω-Transaminases
✍ Dominik Koszelewski; Iván Lavandera; Dorina Clay; David Rozzell; Wolfgang Krouti 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 247 KB 👁 1 views

## Abstract Various ω‐transaminases were tested for the synthesis of enantiomerically pure amines from the corresponding ketones employing D‐ or L‐alanine as amino donor and lactate dehydrogenase to remove the side‐product pyruvate to shift the unfavourable reaction equilibrium to the product side.