Long-term treatment with levodopa in Parkinson's disease results in the development of motor fluctuations, including reduced duration of antiparkinsonian action and involuntary movements, i.e., levodopa-induced dyskinesia. Cannabinoid receptors are concentrated in the basal ganglia, and stimulation
μ- and δ-Opioid Receptor Antagonists Reduce Levodopa-Induced Dyskinesia in the MPTP-Lesioned Primate Model of Parkinson's Disease
✍ Scribed by Brian Henry; Susan H. Fox; Alan R. Crossman; Jonathan M. Brotchie
- Book ID
- 115607569
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 75 KB
- Volume
- 171
- Category
- Article
- ISSN
- 0014-4886
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