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ΔNp53 or p44: priming the p53 pump

✍ Scribed by Heidi Scrable; Tsutomu Sasaki; Bernhard Maier

Book ID
116306920
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
229 KB
Volume
37
Category
Article
ISSN
1357-2725

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## Abstract The E6 and E7 proteins of human papillomaviruses (HPV) play a crucial role in the pathogenesis of malignant tumors. E6 protein of high‐risk mucosal papillomaviruses targets a number of proteins for proteosomal degradation through complex formation with ubiquitin ligase E6AP. These prote