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δ-Subunit containing GABAA receptor knockout mice are less sensitive to the actions of 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridin-3-ol

✍ Scribed by Stephen L. Boehm II; Gregg E. Homanics; Yuri A. Blednov; R. Adron Harris

Book ID: 113586057
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 173 KB
Volume: 541
Category: Article
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2006.02.054

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## Abstract GABA~A~ agonist‐induced formation of low‐affinity GABA~A~ receptors in cultured cerebellar granule cells was studied in the presence or absence of α‐difluoromethylornithine (DFMO), a blocker of polyamine formation. High‐ and low‐affinity GABA~A~ receptors were monitored by Scatchard ana