γδ T cells develop, respond and survive – with a little help from CD27

✍ Scribed by Willi K. Born; Rebecca L. O'Brien

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 125 KB
Volume: 41
Category: Article
ISSN: 0014-2980
DOI: 10.1002/eji.201041270

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In animal models, lymphocytic choriomeningitis virus (LCMV) may be controlled after acute infection or may establish various levels of persistence. Cytotoxic responses mediated by CD8(+) T cells are responsible for both initial control of LCMV and for immunopathology. As discussed in this article, t