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γH2AX and cancer

✍ Scribed by Redon, Christophe E.; Dickey, Jennifer S.; Nakamura, Asako J.; Sedelnikova, Olga A.; Solier, Stéphanie; Pommier, Yves; Bonner, William M.


Book ID
109948212
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
716 KB
Volume
8
Category
Article
ISSN
1474-1776

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## Abstract Recent findings reveal that chromatin reorganization requires formation and repair of DNA double strand breaks (DSBs). Therefore, dynamic changes in chromatin structure taking place along the mitotic and the meiotic processes should be accompanied by histone H2AX phosphorylation and for