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γ-Sulphenylation of αβ-unsaturated aldehydes, ketones, and esters: the use of O-silylated dienolates

✍ Scribed by Ian Fleming; Jon Goldhill; Ian Paterson


Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
226 KB
Volume
20
Category
Article
ISSN
0040-4039

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γ-Alkylation of unsaturated ketones and
✍ Ian Fleming; John Goldhill; Ian Paterson 📂 Article 📅 1979 🏛 Elsevier Science 🌐 French ⚖ 216 KB

The O-silylated dienolates of unsaturated ketones and esters can be alkylated using zinc bromide catalysis to give predominantly the y-alkylated carbonyl compounds. The substitution pattern of the substrate (11, favours, in certain cases, very high or complete y-selectivity.