Objective: The most common pathogenesis for familial Alzheimer's disease (FAD) involves misprocessing (or alternative processing) of the amyloid precursor protein (APP) by c-secretase due to mutations of the presenilin 1 (PS1) gene. This misprocessing/alternative processing leads to an increase in t
✦ LIBER ✦
γ-secretase inhibitors for the treatment of Alzheimer's disease
✍ Scribed by Wen-Lian Wu; Lili Zhang
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 105 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0272-4391
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