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γ-Interferon counteracts interleukin-1α stimulated expression of urokinase-type plasminogen activator in human endothelial cells in vitro

✍ Scribed by Johann Wojta; Hans Zoellner; Marisa Gallicchio; John A. Hamilton; Katherine McGrath


Book ID
115765854
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
579 KB
Volume
188
Category
Article
ISSN
0006-291X

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In LLC-PK, porcine epithelial cells, the urokinase-type plasminogen activator (u-PA) mRNA and protein can be induced either by stimulation of the protein kinase C (PKC) pathway using a tumor promoter (PMA) or by stimulation of the protein kinase A (PKA) pathway with calcitonin SCT). By PKC, to LLC-P