✦ LIBER ✦

γ-Cyclodextrin as chiral mobile phase additive in the HPLC separation of the atropisomers of some N-arylthiazoline-2-thiones and N-arylthiazoline-2-ones: Attempts to quantify the effect of selected structural parameters

✍ Scribed by Dr. Christian Roussel; Anita Favrou

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 770 KB
Volume: 5
Category: Article
ISSN: 0899-0042
DOI: 10.1002/chir.530050613

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✦ Synopsis

The effect of the position and type of the substituent on the chromatographic separation of N-arylthiazoline-2-thione and arylthiazoline-Zone atropisomers are described in reversed-phase HPLC using por y-cyclodextrin as chiral mobile phase additive.

A quantitative approach to experimental design has been developed.